Yes, you can die from an ingrown toenail. How can you die? Simple, the ingrown toenail gets infected leading to a blood infection which leads to Sepsis which leads to death. Has it ever happened? Yes it has happened. Is it common? No the chances are almost zero. The only people that should even be worried about such an event are immunocomprised people such as those with HIV and Diabetes. Those people need to see a Podiatrist ASAP with an ingrown toenail. Most people without comordbidites should still see a Podiatrist but they will not die over an ingrown toenail.